Table 3.

Markers of mineral metabolism and bone mineral density findings at baseline, 12 months, and 24 months post-prophylactic gastrectomy

	Baseline	12-months post-TG	P-valuea	24-months post-TG	P-valueb	P-valuec
Serum calcium, mean ± SD, mmol/L	2.35 ± 0.12	2.36 ± 0.11	.978	—	—
Serum phosphorus, mean ± SD, mg/dL	3.52 ± 0.53	3.64 ± 0.57	.145	—	—
Serum alkaline phosphatase, ± SD, U/L	68.06 ± 22.0	82.3 ± 23.94	<.001	—	—
Serum 25 (OH)-vitamin D, mean ± SD, ng/mL	34.0 ± 15.54	44.22 ± 12.75	<.001	—	—
Lumbar spine BMD, mean ± SD, g/cm2	1.02 ± 0.14	0.98 ± 0.16	<.001	0.99 ± 0.15	.83	<.001
Femoral neck BMD, mean ± SD, g/cm2	0.83 ± 0.14	0.77 ± 0.12	<.001	0.75 ± 0.12	.002	<.001
Total hip BMD, mean ± SD, g/cm2	0.98 ± 0.17	0.88 ± 0.12	<.001	0.85 ± 0.16	.11	<.001
Lumbar spine T-score, mean ± SD	−0.31 ± 1.29	−0.84 ± 1.42	<.001	−0.62 ± 1.37	.50	<.001
Femoral neck T-score, mean ± SD	−0.31 ± 1.15	−0.90 ± 1.03	<.001	−1.05 ± 1.04	.02	<.001
Total hip T-score, mean ± SD	0.04 ± 1.06	−0.60 ± 0.99	<.001	−0.74 ± 0.97	.008	<.001

Abbreviations: BMD, bone mineral density; TG, total gastrectomy.

paired t-test between baseline and 12 months post-TG.

paired t-test between 12 months and 24 months post-TG.

paired t-test between baseline and 24 months post-TG.