表 2.

MR分析SNPs信息表

Basic information of the single nucleotide polymorphisms (SNPs)

SNPs	chr	EA	OA	EAF	T1DM			Thyrotoxicosis			F
					β	SE	P	β	SE	P
SNPs: Single nucleotide polymorphisms; chr: Chromosome; EA: Effect allele; OA: Other allele; EAF: Effect allele frequency; β: Effect allele value; SE: Standard error; F: Statistics for assessing the impact of weak instrumental variables.
rs10183097	2	C	T	0.1362	0.205	0.032	1.82E-10	-0.009	0.032	0.79	40.651
rs10760335	9	G	A	0.3205	0.136	0.024	2.43E-08	0.038	0.025	0.129	31.185
rs10774624	12	A	G	0.5037	-0.256	0.024	1.34E-25	-0.045	0.024	0.057	109.734
rs10830227	11	A	G	0.5741	0.158	0.023	1.02E-11	0.026	0.023	0.268	46.1
rs10865468	2	C	G	0.2527	-0.162	0.028	4.66E-09	0.016	0.025	0.531	34.373
rs10911399	1	G	A	0.0455	-0.371	0.064	6.75E-09	0.114	0.07	0.107	33.549
rs12722495	10	C	T	0.1122	-0.315	0.041	1.27E-14	-0.062	0.047	0.185	59.418
rs13182737	5	A	G	0.2553	0.147	0.026	1.49E-08	-0.037	0.025	0.148	31.995
rs17125653	14	A	T	0.077	0.236	0.040	4.75E-09	0.021	0.034	0.536	34.319
rs1869449	2	A	G	0.2967	0.177	0.027	4.55E-11	0.002	0.026	0.927	43.246
rs19232474	2	G	T	0.0131	0.562	0.088	1.37E-10	0.262	0.095	0.006	41.253
rs194749	14	C	T	0.2455	-0.164	0.028	5.37E-09	-0.053	0.026	0.041	33.979
rs202520	20	G	A	0.7222	-0.157	0.026	7.97E-10	-0.004	0.024	0.875	37.756
rs206763	6	A	G	0.0202	0.679	0.078	2.93E-18	-0.038	0.094	0.683	76.019
rs2071647	12	A	T	0.2755	0.153	0.026	3.30E-09	0.009	0.026	0.744	34.984
rs2111485	2	G	A	0.6033	0.158	0.025	1.89E-10	0.009	0.023	0.710	40.435
rs2269247	1	T	C	0.1804	0.171	0.030	7.28E-09	-0.003	0.025	0.921	33.561
rs231971	16	G	A	0.1026	0.241	0.040	1.55E-09	0.105	0.060	0.083	36.513
rs34296259	9	A	T	0.0082	0.664	0.117	1.43E-08	-0.039	0.052	0.459	32.124
rs34536443	19	C	G	0.0515	-0.412	0.067	4.84E-10	-0.045	0.067	0.499	38.739
rs4566101	15	C	T	0.2697	0.176	0.026	6.23E-12	0.007	0.026	0.778	47.367
rs506770	6	C	G	0.768	1.005	0.043	3.33E-123	0.092	0.028	0.001	556.34
rs55996894	14	C	G	0.204	-0.179	0.032	3.13E-08	-0.037	0.033	0.251	30.540
rs59680223	12	T	C	0.0081	0.642	0.103	5.00E-10	0.135	0.093	0.146	38.712
rs62410259	4	A	G	0.077	-0.380	0.053	1.02E-12	-0.038	0.043	0.371	50.722
rs6719660	2	G	A	0.9354	0.292	0.052	2.52E-08	-0.024	0.059	0.690	31.010
rs689	11	T	A	0.7109	0.700	0.035	2.30E-87	-0.003	0.029	0.920	391.459
rs6909461	6	C	A	0.2529	-0.314	0.033	3.06E-21	0.011	0.030	0.722	89.451
rs741172	16	T	C	0.3205	-0.203	0.026	3.11E-15	-0.029	0.026	0.249	62.153
rs8056814	16	A	G	0.0793	0.264	0.042	1.99E-10	0.094	0.042	0.0246	40.499
rs9273363	6	A	C	0.3317	1.279	0.033	1.00E-200	0.108	0.027	5.91E-05	1465.47
rs9468618	6	T	C	0.0975	-0.301	0.049	7.53E-10	-0.301	0.050	0.230	37.864