Table 4.
Univariate and multivariate Cox regression model for DFS in overall BC patients
| Univariate analysis | Multivariate Cox regression model* | |||
|---|---|---|---|---|
| HR (95% CI) | P | HR (95% CI) | P | |
| Age/years (24–89) | 0.975 (0.952–1.000) | 0.048 | 0.950 (0.928–0.972) | <0.001 |
| Tumor size/cm (0.3–10) | 1.261(1.049–1.514) | 0.013 | ns | ns |
| Grade 1 | Ref | Ref | ||
| 2 | ns | ns | ns | ns |
| 3 | 0.443 (0.260–0.753) | 0.003 | ns | ns |
| Hormone receptor status (− vs +) | 0.423 (0.237–0.758) | 0.004 | 3.342 (1.658–6.736) | 0.001 |
| Postoperative endocrine therapy (− vs +) | 0.117 (0.064–0.214) | <0.001 | 0.048 (0.048–0.023) | <0.001 |
BC breast cancer; DFS disease-free survival; HR hazard ratio; 95% CI 95% confidence interval; Ref reference; ns not statistically significant
*Variables that were significant in univariate analysis (P < 0.05) were included in multivariate Cox analysis, and other non-significant clinical parameters not shown