Table 4.
Results of sentinel node analysis in Breast-conserving therapy
| Parameter | Histology n = 25,046 | % | OSNA n = 711 | % | P-value |
|---|---|---|---|---|---|
| Macrometastasis | 2522 | 10.1 | 51 | 7.2 | 0.011 |
| Micrometastasis | 1723 | 6.9 | 104 | 14.6 | < 0.001 |
| Axillary therapy* | 0.046 | ||||
| Yes | 3218 | 12.8 | 80 | 11.3 | |
| No | 21,673 | 86.5 | 631 | 88.7 | |
| Unknown | 155 | 0.6 | 0 | 0.0 | |
| Axillary lymph node dissection | 278 | 1.1 | 4 | 0.6 | 0.167 |
| Axillary radiotherapy | 0.072 | ||||
| Yes | 2940 | 11.7 | 76 | 10.7 | |
| No | 21,951 | 87.6 | 635 | 89.3 | |
| Unknown | 155 | 0.6 | 0 | 0.0 | |
| Chemotherapy** | 4184 | 16.7 | 133 | 18.7 | 0.159 |
| Endocrine therapy | 11658 | 46.5 | 286 | 40.2 | 0.001 |
| Chemotherapy and endocrine therapy | 2973 | 11.9 | 67 | 9.4 | 0.046 |
| cT stage | 0.072 | ||||
| T1a/b | 7401 | 29.6 | 234 | 32.9 | |
| T1c | 12,702 | 50.7 | 360 | 50.6 | |
| T2 | 4476 | 17.8 | 104 | 14.6 | |
| T3 | 60 | 0.2 | 0 | 0.0 | |
| Tx | 407 | 1.6 | 13 | 1.8 |
Significant differences are bold
*Axillary lymph node dissection or axillary radiotherapy
**Chemotherapy with or without (targeted) immunotherapy. Statistical analysis was performed using Pearson Chi-square test