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. 2023 Sep 1;14:1260973. doi: 10.3389/fimmu.2023.1260973

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Copyright © 2023 Alberro-Brage, Kryvenko, Malainou, Günther, Morty, Seeger, Herold, Samakovlis and Vadász

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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mRNA expression in AEC and BAL fluid cells from IV-infected mice. (A) Top 50 differentially expressed genes (DEG) in AEC. (B) mRNA levels of the top 6 most expressed LDL receptor family members in AEC. (C, D) Tgfb1 mRNA levels in AEC (C) and BAL fluid cells (D). (E) mRNA levels of clathrin (Cltc) and caveolin-1 (Cav-1) in AEC. (F) mRNA expression levels of the albumin receptors megalin, secreted protein acidic and rich in cysteine (Sparc), the scavenger receptor Cd36, and neonatal Fc receptor (Fcgrt) in mock and infected (IV) AEC. Expression levels or transferrin receptor (TFr) are shown for comparison. Normalized RNAseq data, n=3. Bars represent mean ± SD. TPM: transcripts per million. **p<0.01; ***p<0.005.