Table 3.
Groups | Treatment and Dose (mg/kg) | Islet number (N/10 mm2) | Islet area (μm2) |
---|---|---|---|
I | Normal (0.9% NaCl) | 10 ± 0.97 | 27.36 ± 2.793 |
II | Streptozotocin (50 mg/kg i.p) | 2.16 ± 0.19 a | 10.968 ± 1.388 a |
III | STZ + Glimepiride (0.5 mg/kg, p.o.) | 7 ± 0.87 a** | 12.464 ± 1.957 a** |
IV | STZ + P. juliflora (200 mg/kg, p.o.) | 6 ± 0.53 a** | 22.395 ± 2.035 a** |
V | STZ + P. juliflora (400 mg/kg, p.o.) | 9 ± 0.98 a** | 25.214 ± 3.769 a** |
The data were expressed in Mean ± S.E.M; n = 8 in each group; Values were considered statistically significant at (a**p< 0.001) when compared to Group II; (ap< 0.001) significant when compared to Group I. Data were analysed using a one-way ANOVA test followed by Tukey’s HSD test.