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. 2023 Sep 1;14:1215302. doi: 10.3389/fimmu.2023.1215302

Table 3.

Overview of clinical studies which administered a booster dose of Ad26.ZEBOV.

Study phase Study number Location Population Method Booster dose administration
Phase 2 EBL2002 Burkina Faso, Côte D’Ivoire, Kenya Uganda • Healthy adults
• HIV-infected adults
• 4–11 years
• 12–17 years
Randomized, placebo-controlled, observer-blind • 1 year
EBL2011 Sierra Leone • 1–3 years
• 4–11 years
Open label • 3.1 years
• 3.8 years
Phase 3 EBL3001 Sierra Leone • Healthy adults Staged study with an open-label, uncontrolled Stage 1 followed by a randomized, controlled, double-blind Stage 2 • 2 years

HIV, human immunodeficiency virus.