Table 2.
Logistic regression analyses for the association between ALT/HDL-C ratio, AST/HDL-C ratio, GGT/HDL-C ratio and NAFLD.
| Odds ratios (95% confidence interval) | ||||
|---|---|---|---|---|
| Unadjusted model | Model 1 | Model 2 | Model 3 | |
| ALT/HDL-C ratio (Per SD increase) | 8.61 (7.80, 9.51) | 3.30 (2.96, 3.67) | 3.23 (2.90, 3.60) | 3.05 (2.63, 3.53) |
| AST/HDL-C ratio (Per SD increase) | 5.47 (4.99, 6.00) | 2.02 (1.82, 2.23) | 1.96 (1.77, 2.17) | 1.45 (1.30, 1.62) |
| GGT/HDL-C ratio (Per SD increase) | 2.41 (2.29, 2.53) | 1.38 (1.31, 1.45) | 1.43 (1.35, 1.50) | 1.20 (1.14, 1.27) |
| ALT/HDL-C ratio (Quartile) | ||||
| Quartile 1 | Ref | Ref | Ref | Ref |
| Quartile 2 | 3.05 (2.26, 4.12) | 2.01 (1.47, 2.75) | 1.99 (1.46, 2.73) | 1.83 (1.34, 2.51) |
| Quartile 3 | 10.71 (8.15, 14.07) | 4.39 (3.27, 5.89) | 4.32 (3.22, 5.80) | 3.68 (2.73, 4.96) |
| Quartile 4 | 55.53 (42.58, 72.42) | 14.60 (10.87, 19.61) | 14.34 (10.66, 19.28) | 9.96 (7.32, 13.57) |
| P-trend | <0.0001 | <0.0001 | <0.0001 | <0.0001 |
ALT/HDL-C ratio: alanine aminotransferase to high-density lipoprotein cholesterol ratio; SD: standard deviation; NAFLD: non-alcoholic fatty liver disease.
Model 1 adjusted for age, sex, height and BMI;
Model 2 adjusted for age, sex, height, BMI, exercise habits, smoking status and drinking status;
Model 3 adjusted for age, sex, height, BMI, exercise habits, smoking status, drinking status, AST, GGT, TC, TG, FPG, HbA1c and SBP.
In the analysis of AST/HDL-C ratio and GGT/HDL-C ratio and NAFLD in Model 3, the variables themselves were not adjusted.