Table 3.
Stratified associations between ALT/HDL-C ratio and NAFLD by age, gender, WC and exercise habits.
| Subgroup | No. of participants | No. of cases | unadjusted OR (95%CI) | adjusted 0R (95%CI) | P-interaction |
|---|---|---|---|---|---|
| Age (years) | 0.0106 | ||||
| 18-44 | 8296 | 1319 (15.90%) | 7.66 (6.79, 8.66) | 2.58 (2.20, 3.03) | |
| 45-59 | 5311 | 1081 (20.35%) | 11.22 (9.40, 13.39) | 4.09 (3.29, 5.09) | |
| ≥60 | 635 | 107 (16.85%) | 11.56 (6.21, 21.50) | 4.62 (2.48, 8.60) | |
| Gender | <0.0001 | ||||
| Female | 6840 | 478 (6.99%) | 4.22 (3.28, 5.43) | 1.18 (1.08, 1.30) | |
| Male | 7402 | 2029 (27.41%) | 7.31 (6.49, 8.24) | 3.56 (3.05, 4.16) | |
| Abdominal obesity | 0.0236 | ||||
| Yes | 1853 | 903 (48.73%) | 1.10 (1.09, 1.11) | 1.06 (1.05, 1.08) | |
| No | 12389 | 950 (7.67%) | 1.10 (1.10, 1.11) | 1.05 (1.04, 1.06) |
ALT/HDL-C ratio, alanine aminotransferase to high-density lipoprotein cholesterol ratio; OR, Odds ratios; CI, confidence interval; BMI, body mass index.
Models adjusted for the same covariates as in model 3 ( Table 2 ), except for the stratification variable; Abdominal obesity was defined as a waist circumference ≥90 cm in meles or ≥80 cm in females as a cut-off.