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. 2023 Sep 1;10:1221013. doi: 10.3389/fnut.2023.1221013

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Copyright © 2023 Pipitone, Zito, Gambino, Di Maria, Javed, Lupo, Giglia, Sardo, Ferraro, Rappa, Carlisi, Di Majo and Grimaudo.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Representative images of the histological evaluation of the liver parenchyma on hematoxylin and eosin staining. [(A, B) Control NPD; (C, D) HFD; (E, F) HFD/RT; (G, H) HFD/GT]. (A, C, E, G) Magnification 200×, scale bar 50 μm. (B, D, F, H) Magnification 400×, scale bar 20 μm. (I) Percentage of steatosis. Data are presented as the mean ± SD. NPD vs HFD: p < 0.001, NPD vs HFD/RT: p < 0.001; NPD vs HFD/GT: p < 0.001; HFD vs HFD/RT: p < 0.001; HFD vs HFD/GT: p < 0.001; HFD/RT vs HFD/GT: p < 0.01.