Table 5.
Effect of FNC on the Liver and Kidney Parameters
| LFT (Liver function test) | ||||
|---|---|---|---|---|
| C | F-1 | F-10 | F-25 | |
| Serum alkaline phosphate (ALP) (IU/L) | 187±9.75 | 161±5.05* | 158±6.9* | 151±8.55* |
| Serum total protein (gm/dl) | 6.9±0.445 | 7.6±0.28 | 7.8±0.49 | 8±0.6 |
| Serum albumin (gm/dl) | 3.7±0.285 | 3.1±0.255 | 3.9±0.295 | 4.3±0.315 |
| Serum globulin (gm/dl) | 3.2±0.26 | 3.9±0.395 | 3.7±0.385 | 4.5±0.425 |
| SGOT (AST) (IU/L) | 99±8.26299±17.95 | 140±5.12*340±13.5* | 198±11.09*398±15.05* | 218±7.22*418±17.9 * |
| SGPT (ALT) (IU/L) | 91±2.55 | 87±5.35 | 93±3.65 | 89±5.45 |
| Bilirubin total (mg/dl) | 3.4±0.57 | 2.9±0.245 | 0.9±0.145* | 0.8±0.07 * |
| Bilirubin direct (mg/dl) | 0.9±0.06 | 0.8±0.05 | 0.3±0.012 | 0.2±0.02 |
| Bilirubin indirect (mg/dl) | - | - | - | 0.6±0.03 |
| Van den Bergh reaction | Positive | Positive | Negative | Negative |
| Anti-mitochondrial antibody (M2) U/ml | Negative | Negative | Negative | Negative |
| RFT (Renal function test) | ||||
| Urea (mg/dl) | 38.7±1.735 | 37.4±1.67 | 42.3±2.415 | 43.6±2.68 |
| Blood urea nitrogen (BUN) (mg/dl) | 18.08±0.904 | 20.37±1.0185 | 21.14±1.357 | 23.12±1.456 |
| Creatinine (mg/dl) | 0.38±0.029 | 0.38±0.009 | 0.36±0.028 | 0.41±0.0405 |
| Sodium (mEq/L) | 134.6±7.73 | 125.2±4.26 | 146.7±9.335 | 138.7±7.935 |
| Potassium (mEq/L) | 6.8±0.54 | 6.2±0.41 | 6.9±0.245 | 6.3±0.615 |
| Chloride (mEq/L) | 95.3±7.765 | 93.6±3.68 | 104.2±6.21 | 103.7±4.185 |
| Calcium (mg/dl) | 9.1±0.255 | 10.3±0.415 | 10.3±0.315 | 7.3±0.165 |
| Phosphorus (mg/dl) | 4.7±0.135 | 5.4±0.17 | 6.1±0.405 | 4±0.4 |
| Uric acid (mg/dl) | 5.2±0.16 | 3.2±0.46 | 5.3±0.365 | 3.9±0.395 |
| Cholesterol (mg/dl) | 101±5.05 | 79±4.95* | 96±3.3 | 92±5.6* |
Data represent mean ± SD of the group. The data were analysed using one-way ANOVA followed by Tuckeypost-test. Significant at p<0.05%.