Table 3.

Comparison of Diagnostic Parameters for the Detection of Upper Gastrointestinal Lesions

Diagnostic parameters	WLE vs. CLE	WLE+WLE based biopsy vs. CLE+ CLE-target biopsy	CLE vs. CLE-target biopsy
True Positive (n)	57	51	59
True Negative (n)	0	21	30
False Positive (n)	33	15	0
False Negative (n)	0	3	1
Sensitivity (%)	100	94.4	98.33
(95% CI)	(93.73-100)	(84.61-98.84)	(91.06-99.96)
Specificity (%)	----	58.33	100
(95% CI)		(40.76-74.49)	(88.43-100)
Positive predictive value (%)	-----	77.27	100
(95% CI)		(65.30-86.69)	(93.94-100)
Negative predictive value (%)	-----	87.5	96.77
(95% CI)		(67.64-97.34)	(83.30-99.92)
Accuracy (%)	63.33	80	98.89
(95% CI)	(52.51-73.25)	(70.25-87.69)	(93.96-99.7)

CI, Confidence interval; CLE, Confocal laser endomicroscopy; WLE, White light endoscopy