Table 3A.
Enriched Functions of the Target Genes of the Upregulated miRNAs
| GO terms: Upregulated genes | P-Value | FDR* | ER* | Genes overlap |
|---|---|---|---|---|
| Biological process (BP) | ||||
| GO:0051270: Regulation of cellular component movement | <2.2e-16 | <2.2e-16 | 6.44 | 35 |
| GO:2000145: Regulation of cell motility | 2.20E-16 | <2.2e-16 | 6.43 | 32 |
| GO:0040012: Regulation of locomotion | <2.2e-16 | <2.2e-16 | 5.4 | 34 |
| GO:0033993: Response to lipid | <2.2e-6 | <2.2e-16 | 5.17 | 32 |
| GO:0009628: Response to abiotic stimulus | <2.2e-6 | <2.2e-6 | 6.4 | 35 |
| GO:0010941: Regulation of cell death | <2.2e-16 | <2.2e-16 | 4.63 | 44 |
| GO:0051240: Positive regulation of multicellular organismal process | <2.2e-16 | <2.2e-16 | 4.38 | 42 |
| GO:1902531: Regulation of intracellular signal transduction | <2.2e-16 | <2.2e-16 | 4.37 | 46 |
| GO:0044093: Positive regulation of molecular function | <2.2e-16 | <2.2e-16 | 4.34 | 43 |
| GO:0006915: Apoptotic process | <2.2e-16 | <2.2e-16 | 4.26 | 47 |
| Cellular Component (CC) | ||||
| GO:0000307: Cyclin-dependent protein kinase holoenzyme complex | 3.36E-08 | 7.8974E-06 | 31.397 | 6 |
| GO:1902554: Serine/threonine protein kinase complex | 1.47E-07 | 0.000024689 | 17.463 | 7 |
| GO:1902911: Protein kinase complex | 5.80E-07 | 0.000072327 | 14.303 | 7 |
| GO:0000781: Chromosome, telomeric region | 3.36E-07 | 0.000049345 | 12.003 | 12 |
| GO:0005667: Transcription factor complex | 8.82E-08 | 0.000017281 | 7.2524 | 16 |
| GO:0044454: Nuclear chromosome part | 2.80E-09 | 0.000001096 | 6.4164 | 16 |
| GO:0000228: Nuclear chromosome | 9.37E-10 | 5.51E-07 | 6.3653 | 17 |
| GO:0000785: Chromatin | 6.16E-07 | 0.000072327 | 5.4796 | 13 |
| GO:0044427: Chromosomal part | 4.32E-10 | 5.08E-07 | 5.0852 | 21 |
| GO:0005694: Chromosome | 4.86E-09 | 1.4285E-06 | 4.4433 | 21 |
| Molecular Function (MF) | ||||
| GO:0097472: Cyclin-dependent protein kinase activity | 1.40E-09 | 4.69E-07 | 33.194 | 7 |
| GO:0004674: Protein serine/threonine kinase activity | 3.47E-08 | 7.2425E-06 | 5.8614 | 15 |
| GO:0004672: Protein kinase activity | 7.41E-11 | 6.95E-08 | 5.6772 | 21 |
| GO:0008134: Transcription factor binding | 3.94E-10 | 1.85E-07 | 5.5001 | 20 |
| GO:0019900: Kinase binding | 5.71E-11 | 6.95E-08 | 5.4289 | 22 |
| GO:0000987: Proximal promoter sequence-specific DNA binding | 3.93E-08 | 7.3845E-06 | 5.3676 | 16 |
| GO:0019901: Protein kinase binding | 2.25E-09 | 6.04E-07 | 5.283 | 19 |
| GO:0016773: Phosphotransferase activity, alcohol group as acceptor | 3.59E-10 | 1.85E-07 | 4.9297 | 22 |
| GO:0016301: Kinase activity | 1.50E-09 | 4.69E-07 | 4.568 | 22 |
| GO:0016772: Transferase activity, transferring phosphorus-containing groups | 5.53E-09 | 1.2984E-06 | 4.0639 | 23 |
*FDR, False discovery rate; ER, Enrichment ratio