Table 4.
Intercorrelations of Marker Expression in Patients of Metastatic PCa (n=45) by Pearson Correlation Analysis
| Age | PSA | Gleason G | ROS | apop | Testo | TNF-α | IL-6 | miR21 | miR10b | Cyt-c | BCL2 | BAX | Caspase | Procaspase | SMAC | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Age | 1 | |||||||||||||||
| PSA | 0.169 (0.27) |
|||||||||||||||
| Gleason | -0.095 (0.537) |
0.292* (0.01) |
1 | 1 | ||||||||||||
| ROS | 0.091 (0.552) |
-0.16 (0.295) |
0.175 (0.252) |
|||||||||||||
| Apoptosis | 0.068 (0.656) |
0.345* (0.02) |
0.079 (0.604) |
0.286* (0.05) |
1 | |||||||||||
| Testosterone | -0.243 (0.108) |
-0.007 (0.964) |
-0.006 (0.966) |
0.039 (0.797) |
0.014 (0.928) |
1 | ||||||||||
| TNF-α | 0.02 (0.897) |
0.147 (0.335) |
-0.106 (0.488) |
-0.231 (0.127) |
0.305* (0.042) |
-0.075 (0.625) |
1 | |||||||||
| IL-6 | 0.165 (0.28) |
0.313* ( 0.03) |
-0.068 (0.65) |
-0.163 (0.28) |
0.145 (0.34) |
0.191 (0.2) |
0.149 (0.329) |
1 | ||||||||
| miR 21 | 0.063 (0.682) |
0.029 (0.849) |
0.13 (0.395) |
0.03 (0.845) |
0.019 (0.899) |
0.239 (0.114) |
-0.075 (0.622) |
-0.116 (0.447) |
1 | |||||||
| miR 10b | 0.066 (0.667) |
-0.119 (0.438) |
0.016 (0.918) |
0.064 (0.677) |
0.06 (0.698) |
0.156 (0.305) |
-0.058 (0.704) |
-0.068 (0.658) |
0.111 (0.468) |
1 | ||||||
| Cyto C | 0.232 (0.126) |
-0.188 (0.215) |
0.189 (0.213) |
0.254 (0.092) |
-0.052 (0.732) |
-0.253* (0.043) |
0.069 (0.655) |
0.016 (0.918) |
0.11 (0.472) |
0.023 (0.879) |
1 | |||||
| BCL2 | 0.074 (0.628) |
0.058 (0.705) |
0.114 (0.455) |
0.209 (0.168) |
-0.106 (0.489) |
0.317* (0.034) |
0.212 (0.162) |
0.14 (0.358) |
0.184 (0.226) |
0.049 (0.75) |
0.224 (0.139) |
1 | ||||
| BAX | -0.094 (0.541) |
-0.003 (0.982) |
0.11 (0.472) |
0.034 (0.825) |
0.101 (0.51) |
-0.005 (0.972) |
-0.02 (0.897) |
0.021 (0.893) |
-0.033 (0.829) |
0.172 (0.257) |
-0.129 (0.398) |
0.154 (0.314) |
1 | |||
| Caspase | 0.134 (0.381) |
-0.138 (0.367) |
0.012 (0.935) |
0.101 (0.509) |
-0.068 (0.659) |
0.072 (0.638) |
-0.145 (0.342) |
0.108 (0.48) |
0.006 (0.97) |
0.26* (0.035) |
0.083 (0.589) |
0.13 (0.396) |
0.183 (0.228) |
1 | ||
| Procaspase | -0.058 (0.707) |
-0.126 (0.41) |
0.101 (0.509) |
0.169 (0.268) |
-0.116 (0.447) |
-0.053 (0.728) |
0.014 (0.925) |
-0.065 (0.67) |
-0.128 (0.401) |
-0.115 (0.452) |
0.085 (0.579) |
0.236 (0.119) |
0.25 (0.028) |
0.213 (0.161) |
1 | |
| SMAC | -0.152 (0.319) |
0.026 (0.867) |
-0.036 (0.813) |
-0.101 (0.51) |
-0.014 (0.93) |
0.07 (0.646) |
-0.028 (0.855) |
-0.054 (0.724) |
-0.137 (0.369) |
0.049 (0.751) |
0.049 (0.748) |
0.277 (0.05) |
0.046 (0.766) |
0.005 (0.971) |
-0.116 -0.448 |
1 |
*- P < 0.05, **- P < 0.0