Table 5.

Diagnostic Accuracy of Different Markers in the Diagnosis of Localized PCa and Metastatic PCa Cases Using ROC Curve Analysis

Area Under the Curve
Test Result Variable(s)	Area	Std. Errora	Asymptotic Sig.b	Asymptotic 95% Confidence Interval
				Lower Bound	Upper Bound
ROS	0.992	0.006	0	0.979	1
apop	0.914	0.031	0	0.852	0.975
Testo	0.825	0.044	0	0.739	0.91
TNF-α	0.939	0.028	0	0.885	0.993
IL-6	1	0	0	1	1
miR21	0.613	0.06	0.065	0.496	0.73
miR10b	0.523	0.061	0.71	0.402	0.643
Cyt-C	0.625	0.059	0.042	0.509	0.74
BCL2	0.742	0.059	0	0.626	0.858
BAX	0.022	0.012	0	0	0.045
Caspase-3	0.278	0.053	0	0.174	0.382
Caspase-9	0.4	0.06	0.102	0.283	0.517

The test result variable(s): apop, Testo, TNF, miR21, miR10b, CytC, BCL2, BAX, Caspase-3 and Caspase-9 has at least one tie between the positive actual state group and the negative actual state group. Statistics may be biased; a, Under the nonparametric assumption; b, Null hypothesis: true area = 0.5