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. 2023 Aug 24;14(4):71–85. doi: 10.4291/wjgp.v14.i4.71

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©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved.

This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/

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Distal colon model: Alpha and beta diversity analyses. MiSeq compositional sequencing and bioinformatic analysis were performed to measure the microbiota diversity changes following ADS024 treatment using the: A: Shannon index for alpha diversity; B: Simpson diversity index for alpha diversity; C: UniFrac principal coordinates analysis for beta diversity.