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. 2023 Aug 16;15(17):1095–1107. doi: 10.4155/bio-2023-0078

Table 4. . Recovery of LB-100 and endothall in pooled human plasma.

Analyte [Analyte] (ng/ml) RecoveryAnalyte ± SD RecoveryIS ± SD IS-normalized recovery ± SD
LB-100 7.50 81 ± 11 80 ± 8 101 ± 7
40.0 76 ± 10 72 ± 5 105 ± 6
400 79 ± 11 81 ± 8 98 ± 6
Endothall 7.50 88 ± 9 90 ± 3 98 ± 10
40.0 91 ± 5 94 ± 5 97 ± 2
400 81 ± 3 79 ± 8 104 ± 11

RecoveryAnalyte = [(mean peak area of analyte in plasma matrix)/(mean peak area of analyte in extracted plasma matrix)] × 100%; RecoveryIS = [(mean peak area of IS in plasma matrix)/(mean peak area of IS in extracted plasma matrix)] × 100%; and IS-normalized recovery = (RecoveryAnalyte/ RecoveryIS) × 100%.

IS: Internal standard; RE: Relative error; SD: Standard deviation.