Table 1.
Allelic, Genotypic distribution and logistic regression analysis of significant variants of genes in our study using the MassARRAY platform
| Variant | rs10228682 | rs10069690 | ||
|---|---|---|---|---|
| Nearest gene w.r.t variant | POT1 | TERT | ||
| Polymorphism | C/T | C/T | ||
| Ancestral allele | C | C | ||
| Allele distribution | C | T | C | T |
| Cases | 0.625 | 0.705 | 0.866 | 0.817 |
| Controls | 0.375 | 0.295 | 0.134 | 0.183 |
| Odds ratio at 95% CI | 1.43 (1.09–1.88) | 0.7(0.49–1.00) | ||
| Total HWE | 0.111 | 0.951 | ||
| Genotypic model | Dominant | Recessive | ||
| (CC + CT vs TT) | (CC vs TT + CT) | |||
| p-Value* | 0.002 | 0.019 | ||
| Odds ratio at 95% CI | 1.88 (1.25–2.83) | 1.65 (1.08–2.52) | ||
*Adjusted for Age, Gender, and BMI