Table 2.
Allelic, Genotypic distribution and logistic regression analysis of significant variants of genes in our study using Taqman Chemistry
| Variant | rs10069690 | rs2242652 | ||
|---|---|---|---|---|
| Nearest gene w.r.t variant | TERT | TERT | ||
| Polymorphism | C/T | A/G | ||
| Ancestral allele | C | A | ||
| Allele distribution | C | T | A | G |
| Cases | 0.67 | 0.33 | 0.74 | 0.26 |
| Controls | 0.73 | 0.27 | 0.81 | 0.19 |
| Odds ratio at 95% CI | 1.29 (1.01–1.64) | 1.46 (1.12–1.89) | ||
| Total HWE | 0.67 | 0.48 | ||
| Genotypic model | Dominant model | Dominant model | ||
| TT/CT vs CC | GG/AG vs AA | |||
| p-Value* | 0.02 | 0.003 | ||
| Odds ratio at 95% CI | 1.47 (1.06–2.05) | 1.65 (1.18–2.32) | ||
*Adjusted for Age, Gender, and BMI