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. Author manuscript; available in PMC: 2023 Nov 30.
Published in final edited form as: Sci Transl Med. 2023 May 31;15(698):eabo3189. doi: 10.1126/scitranslmed.abo3189

Table 2.

List of proteins enriched in Patients 17 and 21 versus their controls (mother and father/mother, respectively)

PG.Protein Groups Protein name Gene name Mut/Co|signal_log2_ratio Mut/Co|raw_p_value Mut/Co|adjusted_p_value
P02749 Beta-2-glycoprotein 1 APOH 3,90875773 3,9233E-05 0,01752392
P01861 Immunoglobulin heavy constant gamma 4 IGHG4 3,41081457 3,9313E-07 0,0003951
Q02878 60S ribosomal protein L6 RPL6 3,09519982 8,1085E-05 0,02173071
P62424 60S ribosomal protein L7a RPL7A 2,97520531 2,4946E-06 0,00143263
P18124 60S ribosomal protein L7 RPL7 2,90834996 5,5264E-05 0,01815176
P83731 60S ribosomal protein L24 RPL24 2,78639617 5,8732E-05 0,01815176
P16403 Histone H1.2 H1–2 2,72232694 4,4042E-05 0,0177049
P02768 Serum albumin ALB 2,64236248 3,3722E-18 1,3556E-14
P36578 60S ribosomal protein L4 RPL4 2,50022766 3,276E-07 0,0003951
P01876 Immunoglobulin heavy constant alpha 1 IGHA1 2,32067402 3,007E-05 0,01511011
P20591 Interferon-induced GTP-binding protein Mx1 MX1 2,20162951 6,3215E-05 0,01815176
Q6P2Q9 Pre-mRNA-processing-splicing factor 8 PRPF8 1,33941179 1,5549E-06 0,00125012
Q01469 Fatty acid-binding protein 5 FABP5 -2,29088412 5,7962E-05 0,01815176