Table 2.
Influence of Structural Groupings on PPB for PFAS Carboxylates and Sulfonates
| Carboxylates | Sulfonates | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
|
| ||||||||||
| Perfluorinated (Per) | Polyfluorinated (Poly) | Per | Poly | |||||||
| # C |
Per | fup | FT | fup | Poly | fup | Per | fup | FT | fup |
| 3 | PFPA | 0.3108 | -- | -- | -- | -- | -- | -- | ||
| 4 | PFBA | 0.0930 | -- | -- | 4H-PFBA | 0.1714 | PFBS | 0.0046 | -- | -- |
| 5 | PFPeA | 0.0440 | -- | -- | -- | -- | -- | -- | ||
| 6 | PFHxA | 0.0068 | 3:3FTCA | 0.0518 | PFHxS | 0.0009 | 4:2FTS | 0.0050 | ||
| 7 | PFHpA | 0.0004 | -- | -- | 7H-PFHpA | 0.0026 | PFHpS | 0.0006 | -- | -- |
| 8 | PFOA | 0.0010 | 5:3FTCA | 0.0059 | 8H-PFOA | 0.0021 | PFOSa | 0.0045 | 6:2FTS | 0.0143 |
| 9 | PFNA | 0.0016 | 6:3FTCA | 0.0023 | 9H-PFNA | 0.0009 | -- | -- | -- | -- |
| 10 | PFDA | 0.0027 | 7:3FTCA | 0.0051 | PFDS | 0.0528 | 8:2FTS | 0.0396 | ||
| 11 | PFUnDA | 0.0148 | -- | -- | 11H-PFUnDA | 0.0015 | -- | -- | -- | -- |
| 13 | PFTrDA | 0.0433 | -- | -- | -- | -- | -- | -- | ||
| 14 | PFTeDA | 0.0271 | -- | -- | -- | -- | -- | -- | ||
C= carbons; FT=fluorotelomer. Full names for PFAS listed in Table S1. fup = fraction unbound in plasma;
a: PFOS shown as an average of 3 independent values derived for K+ PFOS, PFOS, and PFOS anion. Per and FT comparisons are in bold. PFCAs with at least 11 Cs and that exhibit reduced binding are italicized.