Table 1.

Common Ferroptosis Agonists, Antagonists and Their Regulatory Mechanisms

	Regulatory Mechanism	Representative Compound
Agonist	Inhibiting Xc-System	Sorafenib;34 erastin;35 HO-1;36 glutamate;37 deubiquitylase otub1;38 dihydroorotate dehydrogenase;39 etc.
	Inhibition/degradation of GPX 4	RSL3;40 acetaminophen;41 naringenin;42 etc.
	Others	FINO (2);43 statin;44 ammonium ferric citrate;45 artesunate;46 cyst(e)inase;47 etc.
Antagonists	Inhibits iron accumulation	Ciclopirox olamine;48 Fty720,49 dynasore;50 baicalein;51 etc.
	Inhibition of lipid peroxidation	Hspb1;52 Fsp1;23 Fer-1;53 cycloheximide;54 rapamycin;55 etc.
	Others	Sevoflurane;56 ginsenoside rd;56 etc.