Figure 3.
Rabies virus (RABV)-specific CD4+ and CD8+ T cells 28 days after initial rabies vaccination: Frequencies of antigen-specific (A) CD4+ and (B) CD8+ T cells 28 days after vaccination with rabies vaccine administered Intradermal (ID, green, n = 23) and intramuscular (IM, blue, n = 18), after 24 h stimulation with GlyRab peptide pool. Induced expression of CD25 and OX40 was used to identify RABV-specific CD4+ T cells; and CD137 and CD69 to identify RABV-specific CD8+ T cells. Each dot represents a single individual. Lines represent median and interquartile range. Statistics: Mann–Whitney test. *P < .05.