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. 2023 Feb 23;14(5):594–604. doi: 10.4103/idoj.idoj_418_22

Table 3.

Categories of chronic Lyme disease

Category Description
1 Patients have nonspecific signs and symptoms suggestive of Lyme disease but no objective clinical or laboratory evidence of infection.
2 Patients may have a history of tick exposure with symptoms suggestive of Lyme disease but have an alternative identifiable illness to explain said symptoms.
3 Patients have serological evidence suggestive of Lyme disease but do not have clinical symptoms consistent with Lyme disease.
4 Also referred as post-Lyme disease syndrome, such patients have clinical and laboratory evidence of past Lyme disease but have persistent symptoms of fatigue, pain, and neurocognitive impairment for longer than six months despite appropriate antibiotic therapy.