TABLE 3.
Susceptibility in yeast nitrogen base brotha
| Isolate | N | Putative statusb | MIC (μg/ml)c
|
|||||
|---|---|---|---|---|---|---|---|---|
| 48 h
|
72 h
|
|||||||
| Range | Geo M | Mode | Range | Geo M | Mode | |||
| CN 1 | 10 | S | 0.25–0.5 | 0.43 | 0.5 | 0.5–1 | 0.63 | 0.5 |
| CN 2 | 10 | S | 0.25–1 | 0.5 | 0.5 | 0.5–1 | 0.66 | 0.5 |
| CN 3 | 8 | S | 0.5–1 | 0.6 | 0.5 | 0.5–1 | 0.66 | 0.5 |
| CN 4 | 8 | S | 0.5 | 0.5 | 0.5 | 0.5–1 | 0.82 | 1 |
| CN 5 | 7 | S | 0.25–1 | 0.41 | 0.25 | 0.5–1 | 0.64 | 0.5 |
| CN 6 | 8 | S | 0.25–0.5 | 0.35 | 0.25 | 0.5–1 | 0.64 | 0.5 |
| CN 7 | 8 | S | 0.25–0.5 | 0.42 | 0.5 | 0.5 | 0.5 | 0.5 |
| CN 9 | 11 | S | 0.5–2 | 0.68 | 0.5 | 0.5–1 | 0.75 | 1 |
| CN 12 | 12 | S | 0.25–0.5 | 0.35 | 0.25 | 0.25–0.5 | 0.35 | 0.25 |
| CN 8 | 9 | R | 1.0–2.0 | 1.36 | 1 | 1.0–2.0 | 1.86 | 2 |
| CN 10 | 12 | R | 2 | 2 | 2 | 2 | 2 | 2 |
| CN 11 | 12 | R | 1.0–2.0 | 1.85 | 2 | 1.0–2.0 | 1.74 | 2 |
a
Twelve C. neoformans isolates were tested by the microdilution methodology in broth in YNB. The isolates were tested the indicated number of times (N). MICs were determined after 48 and 72 h of incubation.
b
S, susceptible; R, resistant.
c
Range, range of MICs; Geo M, geometric mean MIC; Mode, modal MIC.