Reaction scheme and gene cluster for the proposed sulfo-ASDO pathway
(A) Gene cluster for the sulfo-ASDO pathway in M. aestuarii and M. ushuaiensis.
(B) The proposed sulfo-ASDO pathway diagram.
(C) AlphaFold model of the active site of SqoD (UniProt A0A1A9EZ58), in which the positions of the Fe and α-ketoglutarate were estimated by overlaying with the crystal structure of E. coli TauD (PDB 1OS7).
(D) Reaction scheme for SqoD. See also Figures S2, S6, and S7 and Table S1.