Table 1.

General parameters and blood measurements of WT and APP/PSN1 animals treated with HFD plus adiponectin or resistin.

	WT	WT+HFD	WT+HFD+ApN	WT+HFD+Resistin
Body weight (g)	31 ± 9	50 ± 8*	54 ± 7*	56 ± 8*
Calories intake (Kcal/day)	24 ± 3	38 ± 5*	41 ± 5*	43 ± 4**
Adiponectin (ug/mL)	15 ± 3	8 ± 2*	19 ± 3*&	8 ± 2*
Resistin (ng/mL)	7 ± 2	17 ± 2*	8 ± 2*	30 ± 5**&
Glucose (mg/dL)	91 ±19	155 ± 23*	93 ± 19&	177 ± 20**
Cholesterol (mg/dL)	132 ± 22	190 ± 21*	126 ± 20	200 ± 28*
Triglycerides (mg/dL)	85 ± 13	140 ± 21**	111 ± 18&	160 ± 19**
Insulin (mg/dL)	1 ± 0.1	3 ± 0.2**	1.3 ± 0.2&	3.5 ± 0.2**
HOMA (mg/dL)	0.2 ± 0.03	1.1 ± 0.1**	0.3 ± 0.1&	1.2 ± 0.1**
	APP/PSN1	APP/PSN1+HFD	APP/PSN1+HFD+ApN	APP/PSN1+HFD+Resistin
Body weight (g)	31 ± 8	56 ± 9*	50 ± 9*	58 ± 8*
Calories intake (Kcal/day)	21 ± 3	42 ± 6**	44 ± 7**	46 ± 6**
Adiponectin (ug/mL)	12 ± 2	6 ± 3*	20 ± 5*&	7 ± 1*
Resistin (ng/mL)	9 ± 2	26 ± 4**	25 ± 5**	45 ± 8**&
Glucose (mg/dL)	97 ± 21	173 ± 15**	105 ± 15&	170 ± 23**
Cholesterol (mg/dL)	123 ± 20	196 ± 22*	145 ± 22	231 ± 38**
Triglycerides (mg/dL)	81 ± 18	156 ± 23**	104 ± 25&	162 ± 25*
Insulin (mg/dL)	0.8 ± 0.1	3.4 ± 0.9**	1.2 ± 0.3&	3.7 ± 0.8**
HOMA (mg/dL)	0.1 ± 0.02	1.5 ± 0.1**	0.5 ± 0.1&	1.7 ± 0.2*

*p < 0.05 and **p < 0.01, compared with WT or APP/PSN1 control groups; ^&p < 0.05, compared with WT or APP/PSN1 + HFD group.