Table 2. General Linear Models for Task Reactivity.
ROI | Variablea | Standardized coefficient, β | t Statistic | Uncorrected P value |
---|---|---|---|---|
Threat task (n = 280) | ||||
Hippocampus | Intercept | NA | −1.86 | .06 |
ADI | 0.15 | 2.30 | .02 | |
Age | 0.05 | 0.87 | .39 | |
Sex | 0.01 | 0.09 | .93 | |
Income | −0.03 | −0.49 | .63 | |
LEC-5 | 0.04 | 0.61 | .54 | |
Amygdala | Intercept | NA | −1.57 | .12 |
ADI | 0.09 | 1.50 | .14 | |
Age | 0.09 | 1.38 | .17 | |
Sex | 0.07 | 1.22 | .23 | |
Income | <−0.01 | −0.04 | .97 | |
LEC-5 | 0.11 | 1.87 | .06 | |
ACC | Intercept | NA | −1.59 | .11 |
ADI | 0.16 | 2.56 | .01 | |
Age | <−0.01 | −0.05 | .96 | |
Sex | −0.01 | −0.24 | .81 | |
Income | <0.01 | <.01 | >.99 | |
LEC-5 | −0.02 | −0.35 | .73 | |
Subgenual ACC | Intercept | NA | −0.77 | .44 |
ADI | 0.02 | 0.26 | .80 | |
Age | 0.04 | 0.67 | .50 | |
Sex | −0.03 | −0.49 | .63 | |
Income | 0.05 | 0.73 | .47 | |
LEC-5 | −0.06 | −0.91 | .37 | |
Insula | Intercept | NA | −1.16 | .25 |
ADI | 0.20 | 3.20 | .001 | |
Age | −0.02 | −0.38 | .70 | |
Sex | −0.04 | −0.73 | .47 | |
Income | 0.01 | 0.17 | .87 | |
LEC-5 | <0.01 | 0.05 | .96 | |
Reward task (n = 244) | ||||
Amygdala | Intercept | NA | 2.76 | .006 |
ADI | −0.07 | −0.91 | .37 | |
Age | −0.10 | −1.34 | .18 | |
Sex | <0.01 | 0.07 | .94 | |
Income | 0.07 | 0.97 | .33 | |
LEC-5 | −0.13 | −2.04 | .04 | |
Nucleus accumbens | Intercept | NA | 2.53 | .012 |
ADI | 0.10 | 1.41 | .16 | |
Age | −0.04 | −0.66 | .51 | |
Sex | −0.04 | −0.62 | .54 | |
Income | 0.08 | 1.17 | .24 | |
LEC-5 | 0.03 | 0.53 | .60 | |
OFC | Intercept | NA | −0.80 | .43 |
ADI | <0.01 | 0.15 | .89 | |
Age | 0.07 | 1.06 | .29 | |
Sex | −0.02 | −0.33 | .74 | |
Income | 0.07 | 1.03 | .31 | |
LEC-5 | −0.05 | −0.75 | .46 | |
ACC | Intercept | NA | −2.32 | .02 |
ADI | 0.05 | 0.80 | .42 | |
Age | 0.05 | 0.79 | .43 | |
Sex | −0.10 | −1.52 | .13 | |
Income | 0.20 | 3.05 | .002 | |
LEC-5 | −0.05 | −0.76 | .45 | |
Insula | Intercept | NA | −1.33 | .18 |
ADI | 0.01 | 0.12 | .91 | |
Age | <−0.01 | −0.02 | .99 | |
Sex | −0.03 | −0.43 | .67 | |
Income | 0.13 | 1.88 | .06 | |
LEC-5 | −0.06 | −0.85 | .40 |
Abbreviations: ACC, anterior cingulate cortex; ADI, Area Deprivation Index; OFC, orbitofrontal cortex; LEC-5, Life Events Checklist for the Diagnostic and Statistical Manual of Mental Disorders (Fifth Edition) (DSM-5); NA, not applicable; ROI, region of interest.
All variables except sex were continuous and defined as per-unit increases.