Table 2.

Breakdown of Treatment-Related Pneumonitis Incidence by Grade According to Common Terminology Criteria for Adverse Events Version 5.0

Pneumonitis Grade Category	Total (N = 102)	Osimertinib Overlapping (n = 22)	Osimertinib Held During RT (n = 80)
None or grade 1	88 (86.3)	20 (90.9)	68 (85.0)
Grade 2+	14 (13.7)	2 (9.1)	12 (15.0)
Pneumonitis by grade
None	86 (84.3)	18 (81.8)	68 (85.0)
Grade 1	2 (2.0)	2 (9.0)	0 (0.0)
Grade 2	9 (8.8)	1 (4.6)	8 (10.0)
Grade 3	3 (2.9)	1 (4.6)	2 (2.5)
Grade 4	0 (0.0)	0 (0.0)	0 (0.0)
Grade 5	2 (2.0)	0 (0.0)	2 (2.5)
Time to grade 2+ pneumonitis, median [range] in mo	3.2 [1.5–6.3]	2.2 [1.6–2.7]	3.4 [1.5–6.3]

Note: All values are n (%) unless otherwise specified.

RT, radiotherapy.