Table 1.
Demographics of 11,494 Young Chinese Adults from the SMCGES Population
| Demographics | IE1 | AD2 | ||
|---|---|---|---|---|
| Total Cases | 511 | 1,550 | ||
| Age, y, mean ± SD | 23.26 ± 7.12 | 21.92 ± 5.18 | ||
| BMI, kg/m2, mean ± SD | 21.00 ± 3.02 | 21.04 ± 3.34 | ||
| n (%) | Chi-square P-value3 | n (%) | Chi-square P-value3 | |
| Sex | ||||
| Male | 125 (24.5%) | 5.862 × 10−2 | 669 (43.2%) | 2.200 × 10−16 |
| Female | 386 (75.5%) | 881 (56.8%) | ||
| BMI, Asian class (kg/m2) | ||||
| Normal (18.5–23.0) | 317 (62.0%) | 5.333 × 10−2 | 914 (59.0%) | 1.224 × 10−3 |
| Underweight (<18.5) | 57 (11.2%) | 200 (12.9%) | ||
| Overweight (>23.0) | 97 (19.0%) | 295 (19.0%) | ||
| NA | 40 | — | 141 | — |
| Parental History of Eczema | ||||
| None | 246 (48.1%) | 2.200 × 10−16 | 725 (46.8%) | 2.200 × 10−16 |
| At least one | 79 (15.5%) | 251 (16.2%) | ||
| Both | 8 (1.57%) | 27 (1.70%) | ||
| NA | 178 | — | 547 | — |
Abbreviations: AD, atopic dermatitis; BMI, body mass index; IE, intrinsic eczema; NA, not available; SMCGES, Singapore/Malaysia Cross-sectional Epidemiology Study; SPT, skin prick test.
IE case is defined to be a subject with a recurrent itchy rash in flexural areas but having a negative SPT response.
AD case is defined to be a subject with positive SPT to either Blomia tropicalis or Dermatophagoides pteronyssinus and the presence of a recurrent itchy rash in flexural areas.
Chi-square test was performed for each indicated variable for IE presentation (IE cases vs. nonallergic noneczema controls) and AD presentation (AD cases vs. nonallergic noneczema controls). Chi-square P-value < 0.001 (adjusted by Bonferroni’s correction) is considered statistically significant and is written in bold.