Table 2.
Variables | Tested, No. | Seronegative (<0.1 IU/mL) |
Seropositive (≥0.1 IU/mL) |
||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
<0.01 IU/mL |
0.01–0.09 IU/mL |
0.1–0.99 IU/mL |
≥1.0 IU/mL |
||||||||||
No. | % | 95% CI | No. | % | 95% CI | No. | % | 95% CI | No. | % | 95% CI | ||
| |||||||||||||
Overall | 2325 | 502 | 22.4 | 19.1–26.0 | 598 | 26.2 | 24.3–28.2 | 808 | 34.7 | 31.1–38.5 | 417 | 16.7 | 14.4–19.3 |
By age group | |||||||||||||
1–2 years | 208 | 26 | 12.9 | 8.8–18.4 | 46 | 22.1 | 15.7–30.1 | 75 | 38.1 | 32.9–43.5 | 61 | 26.9 | 20.1–35.1 |
3–6 years | 422 | 75 | 17.8 | 13.1–23.6 | 99 | 24.0 | 20.1–28.5 | 149 | 34.9 | 30.0–40.1 | 99 | 23.3 | 19.7–27.4 |
7–9 years | 272 | 56 | 21.7 | 14.9–30.4 | 42 | 15.7 | 11.2–21.6 | 73 | 26.8 | 21.1–33.4 | 101 | 35.8 | 28.9–43.4 |
10–14 years | 514 | 173 | 35.5 | 29.9–41.4 | 140 | 27.4 | 23.4–31.9 | 134 | 25.0 | 20.4–30.2 | 67 | 12.1 | 7.7–18.7 |
15–19 years | 475 | 136 | 29.3 | 24.1–35.1 | 165 | 35.4 | 32.1–39.0 | 145 | 29.5 | 24.3–35.3 | 29 | 5.8 | 3.8– 8.7 |
20–24 years | 434 | 36 | 8.1 | 5.4–12.0 | 106 | 24.1 | 20.7–27.9 | 232 | 54.4 | 49.1–59.6 | 60 | 13.4 | 10.1–17.4 |
An antibody concentration of 0.01 IU/mL is the lowest level giving some degree of protection for diphtheria, concentrations ≥0.1 IU/mL are considered a fully protective level of circulating antibodies; antibody concentrations of ≥1.0 IU/mL are associated with long term protection [10].