Ring-opening reactions of 1c with different catalysts.
| Run | Initiator | Catalyst | 1c/Ax/Cat. | Solvent | [1c] (M) | Temperature (°C) | Time (h) | Conversiona (%) | Major fractionb (%) |
|---|---|---|---|---|---|---|---|---|---|
| 1 | A3 | DPP | 100/1/1–15c | Toluene | 1.0 | 90 | 77 | 57 | 66 |
| 2 | A3 | TBD | 100/1/1–5d | Toluene | 1.0 | 90 | 152 | 77 | 60 |
| 3 | A1 | Sn(Oct)2 | 100/1/1 | Toluene | 1.0 | 100 | 36 | >99 | 41 |
| 4 | A1 | Sn(Oct)2 | 100/1/1.5 | Bulk | 100 | 73 | 80 | 38 |
a
Determined using 1H NMR.
b
Determined from SEC chart in Fig. 8a (THF, 30 °C).
c
DPP is gradually loaded up to 15 mol%.
d
TBD is added in the middle of the reaction to be 5 mol%.