Research gaps and deficiencies	Improvement
• Poorly understood precise properties and developmental sources of pericytes • Heterogeneous and a tissue- and context-dependent manner of the origin of pericytes • A tissue- and context-dependent manner for different morphology and expression markers • Confusion and controversial identity when compared with other mural cells, such as smooth muscle cells, fibroblasts, myofibroblasts, due to unavailable single cell marker • The function, characterization, and identification of subtypes of pericytes • Pathological or protective role of pericytes in different disease settings • Maintain a physiological pericyte culture without any lineage change in vitro	• Single-cell RNAseq to identify unique pericyte markers in human vs. other species, such as rodents • Identify pericyte specific markers in different tissues • Creation of pericyte specific Cre-ER transgenic animal model