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. Author manuscript; available in PMC: 2023 Sep 19.
Published in final edited form as: Free Radic Biol Med. 2022 Jun 9;188:134–145. doi: 10.1016/j.freeradbiomed.2022.06.005

Fig. 1. BACH1 deficiency reduces mortality after CLP-induced sepsis.

Fig. 1.

(A) 10-day survival following CLP surgery-induced sepsis represented by Kaplan-Meier curve (n = 10/group) show reduced mortality rate in Bach1−/− mice compare to WT mice. (B) plasma H2O2 levels. (C) liver MPO activity, (D) plasma MDA levels, (E-F), plasma ALT and AST levels. Data scatter plots expressed as mean ± SEM (n = 5–9). (G) Representative histopathological changes of hepatic parenchyma in WT and Bach1−/− mice. KO=Bach1−/−. Statistical significance was defined as p < 0.05. **** = p < 0.0001; *** = p < 0.001; ** = p < 0.01; * = p < 0.05.