Muhafiz 2019.

Study characteristics
Methods	Study design: RCT, parallel‐group design, 3 arms Numbers randomized (total and per group): total 71 participants; 22 in Etafilcon A, 25 in Delefilcon A, 24 in Balafilcon A (monthly reusable lenses, not included in this review) Unit of randomization: person (1 eye per person) Masking: not reported Exclusions and losses to follow‐up (total and per group): not reported Number analyzed (total and per group): 22 in Etafilcon A, 25 in Delefilcon A Unit of analysis (person or eye): person (1 eye per person) Study duration (planned and actual): 3 months Intervention duration: 3 months How were missing data handled: not reported Sample size and power calculation: "Power analysis was conducted using WSSPAS: Web‐Based Sample Size & Power Analysis Software," but details were not reported.
Participants	Country: Turkey Setting: university clinic Inclusion criteria: "Individuals who had not previously used CLs and requested the use of spherical CLs" Exclusion criteria: "Patients were excluded if they had astigmatism over ± 0.5 diopters, if they had a history of CL use, and if they used the CL irregularly" Baseline characteristics Refractive condition: not reported Etafilcon A (N = 22) women (n, %): 19 (86%) age (mean, SD): 21.4 ± 5.3 years race/ethnicity (n, %): not reported habitual wearers (n, %): 0 (0%) Delefilcon A (N = 25) women (n, %): 21 (84%) age (mean, SD): 22.1 ± 6.9 years race/ethnicity (n, %): not reported habitual wearers (n, %): 0 (0%) Total (N = 47) women (n, %): 40 (85%) age (mean, SD, range): 21.77 ± 6.2 years race/ethnicity (n, %): not reported habitual wearers (n, %): 0 (0%) Notes: characteristics of 24 participants in Balafilcon A group (monthly reusable lenses) were not included. "No significant difference was determined between the groups in respect to age and sex (P = 0.05). At the beginning of the study, no statistically significant difference was determined between the groups in respect to the OSDI score, tear osmolarity, TBUT, and Schirmer test (all P = 0.05)"
Interventions	Etafilcon A material: hydrogel replacement frequency: daily disposable Delefilcon A material: silicone hydrogel replacement frequency: daily disposable Notes: participants were instructed to wear SCL for 10 hours every day
Outcomes	Primary outcome: OSDI questionnaire tear osmolarity tear inflammatory cytokines levels TBUT Schirmer test with anesthesia Secondary outcomes: not specified Adverse outcomes (Y/N), if yes, please describe: N Measurement time points: baseline, 1 month, 3 months
Notes	Sponsorship source: "Supported by the Bozok University Scientific Research Projects Unit." Author's name: Ersin Muhafiz, MD Institution: Saglik Bilimleri University Conflicts of interest: "The authors have no conflicts of interest to disclose." Publication language: English Trial register: not reported