NCT01669629.

Methods	RCT, cross‐over design
Participants	Inclusion criteria: between 18 and 45 years of age; willing to wear the study lenses for at least 8 hours per day, 7 days per week; current successful SCL wearer; spherical prescription −1.00 D to −6.00 D; astigmatism less than or equal to 0.75 D; BCVA of 20/30 (6/9) or better Exclusion criteria: ocular or systemic diseases or treatments that may interfere with contact lens wear; clinically significant biomicroscopy findings (Grade 3 or 4); previous hard contact lens use; pregnancy or lactation; no extended wear in the last 3 months
Interventions	Delefilcon A material: silicone hydrogel replacement frequency: daily Etafilcon A material: hydrogel replacement frequency: daily
Outcomes	Primary outcome: participant‐reported ease of removal Secondary outcomes: participant‐reported overall comfort participant‐reported overall vision binocular Snellen VA overall corneal staining
Notes	Sponsorship source: Johnson & Johnson Vision Care Inc. Author's name: Kathy Osborn Institution: Vistakon Comments: whether the analysis accounted for cross‐over design was unclear