NCT03341923.

Methods	RCT, cross‐over design
Participants	Inclusion criteria: age 40 years or older; habitual multifocal SCL silicone hydrogel wearer; requiring a near spectacle addition of +0.50 to +2.50 D; power range +5.00 to −9.00 D; cylinder less than 1.00 D; VA correctable to 20/30 or 0.2 logMAR or better; willing to wear lenses every day (a minimum of 10 days) for 6 hours per day Exclusion criteria: currently wearing study lenses; systemic or ocular disease that contraindicate contact lens wear; use of systemic or ocular medications that contraindicate contact lens wear; monovision; moderate or severe slit lamp findings; refractive surgery; eye injury or surgery within 12 weeks
Interventions	Delefilcon A material: silicon hydrogel replacement frequency: daily Etafilcon A material: hydrogel replacement frequency: daily
Outcomes	Primary outcome: Iens centration (5‐point scale; 0 = optimal/centered and 4 = severe decentration [with corneal exposure]) Secondary outcomes: fluorescein corneal and conjunctival staining (5‐point scale; 0 = normal, 1 = trace, 2 = mild, 3 = moderate, 4 = severe)
Notes	Sponsorship source: Alcon Japan Ltd. Author's name: Alcon Japan Ltd. Institution: Alcon Japan Ltd. Comments: whether the analysis accounted for cross‐over design was unclear