Table V.
The relationship between oxidative stress markers and ANA pattern staining
| Parameter | ANA positive | |||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AC 2 (–) | AC 2 (+) | % change | P-value | AC 21 (–) | AC 21 (+) | % change | P-value | AC4/AC5 (–) | AC4/AC5 (+) | % change | P-value | AC9/AC10 (–) | AC9/AC10 (+) | % change | P-value | |||||||||
| n = 130 | n = 130 | n = 220 | n = 40 | n = 222 | n = 38 | n = 232 | n = 28 | |||||||||||||||||
| Mean | SD | Mean | SD | Mean | SD | Mean | SD | Mean | SD | Mean | SD | Mean | SD | Mean | SD | |||||||||
| Age | 54.7 | 12.3 | 52.8 | 12.6 | –4 | 0.211 | 53 | 12.7 | 57.6 | 10.3 | 9 | 0.033 | 54.2 | 12.5 | 51.2 | 12 | –6 | 0.173 | 53.8 | 12.5 | 53.5 | 12.3 | 0 | 0.915 |
| BMI | 27.5 | 5.07 | 28.5 | 5.12 | 3.70 | 0.111 | 27.83 | 4.78 | 28.97 | 6.61 | 4.10 | 0.195 | 28.4 | 5.16 | 26.02 | 4.37 | –8.20 | 0.009 | 28.1 | 5.26 | 27.3 | 3.69 | –2.70 | 0.46 |
| PSH [µmol/g protein] | 3.72 | 1.13 | 3.65 | 1.18 | –2 | 0.613 | 3.75 | 1.18 | 3.34 | 0.94 | –11 | 0.038 | 3.64 | 1.14 | 3.94 | 1.23 | 8 | 0.131 | 0.7 | 0.75 | 0.55 | 0.36 | –22 | 0.291 |
| TAC [mmol/l] | 1.12 | 0.25 | 1.03 | 0.26 | –8 | 0.007 | 1.06 | 0.27 | 1.14 | 0.22 | 7 | 0.086 | 1.07 | 0.26 | 1.13 | 0.28 | 6 | 0.163 | 10.6 | 2.6 | 10.8 | 2.61 | 2 | 0.755 |
| OSI-index [arbitrary unit] | 0.61 | 0.52 | 0.76 | 0.87 | 25 | 0.092 | 0.67 | 0.74 | 0.75 | 0.63 | 12 | 0.509 | 0.72 | 0.75 | 0.49 | 0.45 | –32 | 0.023 | 3.12 | 1.38 | 3.25 | 1.34 | 4 | 0.651 |
| SOD [NU/ml] | 20.1 | 2.75 | 19.7 | 2.69 | –2 | 0.228 | 19.81 | 2.74 | 20.4 | 2.58 | 3 | 0.203 | 20 | 2.66 | 19.5 | 3.07 | –2 | 0.332 | 3.66 | 1.14 | 3.87 | 1.25 | 6 | 0.369 |
| MnSOD [NU/ml] | 10.52 | 2.52 | 10.8 | 2.68 | 3 | 0.405 | 10.63 | 2.56 | 10.84 | 2.85 | 2 | 0.643 | 10.8 | 2.64 | 10.1 | 2.29 | –6 | 0.144 | 32.3 | 10.8 | 30.9 | 9.57 | –4 | 0.503 |
| CuZnSOD [NU/ml] | 9.57 | 2.71 | 8.91 | 2.48 | –7 | 0.044 | 9.18 | 2.68 | 9.57 | 2.25 | 4 | 0.388 | 9.21 | 2.53 | 9.41 | 3.09 | 2 | 0.662 | 1.08 | 0.26 | 1.06 | 0.28 | –2 | 0.719 |
| UA [µmol/l] | 377 | 87 | 359 | 110 | –5 | 0.035 | 363 | 97 | 395 | 105 | 9 | 0.064 | 368 | 98 | 370 | 104 | 1 | 0.866 | 367 | 101 | 377 | 83.4 | 3 | 0.636 |
AC – anti-cell, ANA – anti-nuclear antibody, BMI – body mass index, OSI-index – oxidative stress index, PSH – protein thiol groups, SOD – superoxide dismutase, TAC – total antioxidant capacity, UA – uric acid.