Search	Query	Total, n
1	‘backache’/de OR ‘failed back surgery syndrome’/de OR ‘discogenic pain’/de OR ‘diskitis’/de OR ‘intervertebral disk degeneration’/de OR ‘lumbar disk hernia’/exp OR ‘low back pain’/de OR ‘musculoskeletal pain’/de OR ‘spondylosis’/de OR ‘spine disease’/de OR ‘vertebral canal stenosis’/de OR ‘lumbar spinal stenosis’/de OR ‘spondylolysis’/de OR ‘spondylosis’/de OR ‘sciatic neuropathy’/de OR ‘back disorder*’ OR ‘back injur*’ OR ‘back sprain*’ OR ‘failed back’ OR ((‘disc’ OR ‘discs’ OR ‘disk’ OR ‘disks’) NEAR/4 (‘herniated’ OR ‘herniation’ OR ‘herniations’ OR ‘degenerative’ OR ‘degeneration’ OR ‘prolapse*’ OR ‘protrusion*’)) OR ((‘lumbar’ OR ‘lumbosacral*’ OR ‘lumbo sacral*’ OR ‘lower back’ OR ‘low back’) NEAR/4 (‘pain’ OR ‘pains’ OR ‘painful’ OR ‘stenosis’ OR ‘stenoses’ OR ‘radiculopath*’ OR ‘instability’ OR ‘instabilities’ OR ‘strain*’ OR ‘strains*’)) OR ‘spondylo*’ OR ‘sciatica’ OR ‘Coccydynia’ OR ‘intervertebral disk’/de OR ‘lumbar vertebra’/de OR ‘fifth lumbar vertebra’/de OR ‘first lumbar vertebra’/de OR ‘forth lumbar vertebra’/de OR ‘second lumbar vertebra’/de OR ‘third lumbar vertebra’/de OR ‘spondylarthritis’/de OR ‘spondyloarthropathy’/de OR ‘spondylolisthesis’/de OR ‘zygapophyseal joint’/de OR ‘back pain*’ OR ‘backache*’ OR ‘back ache*’ OR ‘spinal pain’ OR ‘Zygapophyseal Joint*’ OR ‘Facet joint*’	248715
2	‘manipulative medicine’/exp OR mobilization*:ab,ti OR mobilisation*:ab,ti OR manipulat*:ab,ti OR acupressure:ab,ti OR acupuncture:ab,ti OR ‘applied kinesiology’:ab,ti OR ‘manual therap*’ OR bodywork*:ab,ti OR chiropract* OR massag*:ab,ti OR ‘dry needling’:ab,ti OR reflexolog*:ab,ti	372540
3	‘randomized controlled trial’/exp OR ‘randomized controlled trial topic’/exp OR ‘meta analysis’/exp OR ‘meta analysis topic’/exp OR ‘systematic review topic’/exp OR ‘practice guideline’/exp OR ‘controlled clinical trial’/exp OR randomized:ab,ti OR randomised:ab,ti OR randomization:ab,ti OR randomisation:ab,ti OR placebo:ab,ti OR randomly:ab,ti OR ‘single blind’:ab,ti OR ‘single blinded’:ab,ti OR ‘double blind’:ab,ti OR ‘double blinded’:ab,ti OR systematic:ab,ti OR systematically:ab,ti OR meta-analysis:ab,ti OR meta-synthesis:ab,ti OR meta-analyses:ab,ti OR meta-syntheses:ab,ti OR ‘meta analysis’:ab,ti OR ‘meta synthesis’:ab,ti OR ‘meta analyses’:ab,ti OR ‘meta syntheses’:ab,ti OR metaanalysis:ab,ti OR metaanalyses:ab,ti OR meta-analytic:ab,ti OR ‘meta analytic’:ab,ti OR metaanalytic:ab,ti OR ‘umbrella review’:ab,ti OR ‘umbrella reviews’:ab,ti OR ‘scoping review’:ab,ti OR ‘scoping reviews’:ab,ti OR ‘rapid review’:ab,ti OR ‘rapid reviews’:ab,ti OR ‘practice guideline’:ab,ti OR ‘clinical guideline’:ab,ti OR ((review:ab,ti OR reviews:ab,ti OR reviewed:ab,ti OR search:ab,ti OR searches:ab,ti OR searched:ab,ti OR searching:ab,ti OR handsearch:ab,ti OR handsearched:ab,ti) AND (‘inclusion criteri*’:ab,ti OR ‘exclusion criteri*’:ab,ti OR references:ab,ti OR papers:ab,ti OR articles:ab,ti OR publications:ab,ti OR studies:ab,ti OR trials:ab,ti OR datasets:ab,ti OR databases:ab,ti))	3430175
4	1 AND 2 AND 3	4147