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. 2023 Sep 19;13(40):27801–27827. doi: 10.1039/d3ra05689a

IC50 values of the new compounds 12–17 against Vero normal cells and selectivity indices against the tumor cells.

Comp. Vero cells IC50 (μM) Selectivity index
HT-29 A549 HCT-116
12 422.29 ± 6.17 24.47 22.50
13 425.65 ± 2.42 15.23 21.95 22.69
14 491.03 ± 4.97 22.05 24.79 16.94
15 389.62 ± 2.95 28.73 21.89 28.15
16 123.28 ± 1.44 6.65 4.97 4.26
17 178.8 ± 1.67 3.79 16.42 19.50