Effects of compound 15 and sorafenib on the expression levels of BAX, Bcl-2, caspases-8, and caspases-9 in HT-29 cells.
| Sample | Gene expression (Fold Change) | |||
|---|---|---|---|---|
| BAX | Bcl-2 | Caspase-8 | Caspase-9 | |
| Compound 15/HT-29 | 4.858 ± 0.132a | 0.347 ± 0.033a | 1.701 ± 0.029a | 3.247 ± 0.085a |
| Sorafenib/HT-29 | 4.900 ± 0.20a | 0.316 ± 0.016a | 3.682 ± 0.35a.b | 4.972 ± 0.13a.b |
| Control HT-29 | 1 | 1 | 1 | 1 |
a
Significant P value from control HT-29.
b
Significant P value from compound 15/HT-29, significant P value < 0.05 & by using one-way ANOVA followed by Tukey's post hoc multiple comparison tests.