Table 1.
Baseline characteristics
| Non-Carrier TTR V122I (N=9,529) | Carrier TTR V122I (N=333) | |||
|---|---|---|---|---|
|
| ||||
| N | % or Mean (SD) | N | % or Mean (SD) | |
|
| ||||
| Age at screening, years | 9529 | 61.5 (7.0) | 333 | 61.2 (7.2) |
| 50 – 59 | 3982 | 41.8 | 154 | 46.2 |
| 60 – 69 | 4110 | 43.1 | 129 | 38.7 |
| 70 – 79 | 1437 | 15.1 | 50 | 15.0 |
|
| ||||
| Systolic blood pressure, mmHg | 9528 | 132.1 (17.8) | 333 | 131.5 (18.7) |
| Diastolic blood pressure, mmHg | 9523 | 78.1 (9.4) | 333 | 78.0 (10.2) |
| Heart rate, bpm | 9516 | 70.8 (13.3) | 331 | 70.6 (14.0) |
|
| ||||
| Body mass index, kg/m2 | ||||
| <25 | 1497 | 15.8 | 68 | 20.7 |
| 25 – 30 | 3121 | 33.0 | 115 | 35.0 |
| ≥30 | 4830 | 51.1 | 146 | 44.4 |
|
| ||||
| Smoking status | ||||
| Never | 4541 | 48.6 | 153 | 47.5 |
| Past | 3730 | 39.9 | 126 | 39.1 |
| Current | 1067 | 11.4 | 43 | 13.4 |
| History of hypertension | 5821 | 61.1 | 203 | 61.0 |
| History of CVD (MI/CABG/PCI/CHF/stroke) | 806 | 8.6 | 16 | 5.0 |
| History of diabetes | 1405 | 14.8 | 44 | 13.2 |
|
| ||||
| Physical activity, MET hrs/wk | ||||
| None | 2150 | 23.2 | 78 | 23.6 |
| >0 – 5.0 | 2522 | 27.2 | 93 | 28.2 |
| >5.0 – 14.25 | 2408 | 26.0 | 75 | 22.7 |
| >14.25 | 2197 | 23.7 | 84 | 25.5 |