Table 3.

Clinical and histopathological features of collagenous colitis and non-collagenous colitis cases.

	Collagenous Colitis n=37 (%)	Non-collagenous Colitis n=16 (%)	p
Age ≤50 >50	10 (27) 27 (73)	10 (62.5)  6 (37.5)	0.029
Sex Female Male	26 (70.3) 11 (29.7)	2 (12.5) 14 (87.5)	<0.001
IELs/100 enterocytes 0-4 5-9 10-20 >20	1 (2.7) 21 (56.8) 14 (37.8) 1 (2.7)	3 (18.8) 5 (31.3) 1 (6.3) 7 (43.8)	<0.001
Collagen band (μm) <30 ≥30	27 (73.0) 10 (27.0)	16 (100)  0 (0)	0.021
Lymphoplasmocytosis in lamina propria Slight Moderate/severe	17 (45.9) 20 (54.1)	15 (93.8)  1 (6.3)	0.002
Eosinophils/1HPF in lamina propria 0-19 20-49 ≥50	9 (24.3) 21 (56.8)  7 (18.9)	11 (68.8)  5 (31.3)  0 (0)	0.006
Surface epithelial damage Sloughing Flattening Vacuolization Loss of mucin	27 (73.0) 19 (51.4) 24 (65.0) 23 (62.2)	5 (31.2) 7 (43.7) 5 (31.2) 8 (50.0)	0.006 0.743 0.008 0.214
Entrapped erythrocytes in subepithelial collagen	34 (91.9)	9 (56.3)	0.002
Distinct entrapped cells in subepithelial collagen	20 (54.1)	1 (6.3)	0.001
Neutrophil leukocytes forming cryptitis	3 (8.1)	0 (0)	0.241
Paneth cell metaplasia	6 (16.2)	0 (0)	0.087

*IELs: Intraepithelial lymphocytes, *HPF: High power field