Table 2.
Clinical and histopathological features of MC and MCi cases.
|
|
Collagenous Colitis n=37 (%) |
Lymphocytic Colitis n=7 (%) |
Incomplete Microscopic Colitis n=9 (%) |
p |
|
Age ≤50 >50 |
10 (27.0) 27 (73.0) |
4 (57.1) 3 (42.9) |
6 (66.7) 3 (33.3) |
0.045 |
|
Sex Female Male |
26 (70.3) 11 (29.7) |
0 (0) 7 (100) |
2 (22.2) 7 (77.8) |
<0.001 |
|
IELs/100 enterocytes 0-4 5-9 10-20 >20 |
1 (2.7) 21 (56.8) 14 (37.8) 1 (2.7) |
0 (0) 0 (0) 0 (0) 7 (100) |
3 (33.3) 5 (55.6) 1 (11.1) 0 (0) |
<0.001 |
|
Collagen band (μm) <30 ≥30 |
27 (73.0) 10 (27.0) |
7 (100) 0 (0) |
9 (100) 0 (0) |
0.080 |
|
Lymphoplasmocytosis in lamina propria Slight Moderate/severe |
17 (45.9) 20 (54.1) |
6 (86.0) 1 (14.0) |
9 (100) 0 (0) |
0.003 |
|
Eosinophils/1HPF in lamina propria 0-19 20-49 ≥50 |
9 (24.3) 21 (56.8) 7 (18.9) |
3 (42.9) 4 (57.1) 0 (0) |
8 (88.9) 1 (11.1) 0 (0) |
0.008 |
|
Surface epithelial damage Sloughing Flattening Vacuolization Loss of mucin |
27 (73.0) 19 (51.4) 24 (65.0) 23 (62.2) |
2 (29.0) 6 (86.0) 3 (43.0) 5 (71.0) |
3 (33.0) 1 (11.0) 2 (22.0) 3 (33.0) |
0.014 0.127 0.012 0.087 |
|
Entrapped erythrocytes in subepithelial collagen |
34 (91.9) |
4 (57.1) |
5 (55.6) |
0.006 |
|
Distinct entrapped cells in subepithelial collagen |
20 (54.1) |
1 (14.3) |
0 (0) |
0.003 |
|
Neutrophil leukocytes forming cryptitis |
3 (8.1) |
0 (0) |
0 (0) |
1.000 |
|
Paneth cell metaplasia |
6 (16.2) |
0 (0) |
0 (0) |
0.411 |
*IELs: Intraepithelial lymphocytes, *HPF: High power field.