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. 2022 Dec 13;92(4):762–771. doi: 10.1227/neu.0000000000002260

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Copyright © 2022 The Author(s). Published by Wolters Kluwer Health, Inc. on behalf of the Congress of Neurological Surgeons.

This is an open access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND), where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal.

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FIGURE 3. — A, Time comparison. The average time of AIGS real-time fluorescence PCR detection was 59.2 minutes. The average time of intraoperative rapid histopathological detection was approximately 55.4 minutes. Routine pathological results were available 7 days after the operation, and the average time for NGS detection was 9.2 days. B, Taking the NGS results as the gold standard, the results of AIGS real-time fluorescence PCR were compared with IHC (total = 37). C, Comparison of the diagnosis results of the pathologists in group A and group B in intraoperative histopathological diagnosis. D, Double-blind comparison of AIGS in improving the accuracy of pathologists' intraoperative diagnoses. Compared with group A, group B improved the diagnostic accuracy of glioma by 16.2%, and the diagnostic rate of uncertainty decreased. AIGS, automatic integrated gene detection system; NGS, next-generation sequencing.