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. 2023 Sep 19;18(9):e0291361. doi: 10.1371/journal.pone.0291361

Table 2. Summary of data including the results of the receptors and MMR immunostains, and Fisher’s Exact tests.

Diagnosis n ER PR AR MMR
    +n +% +n +% +n +% +n +%
EEC 36 35 97% 35 97% 35 97% 6 17%
NEEC 26 11 42% 7 27% 17 65% 3 12%
SCA 10 8 80% 5 50% 9 90% 0 0%
CCCA 5 0 0% 0 0% 3 60% 0 0%
CS 5 3 60% 2 40% 5 100% 0 0%
DECA 5 0 0% 0 0% 0 0% 3 60%
MNCA 1 0 0% 0 0% 0 0% 0 0%
Met 4 4 100% 3 75% 4 100% 2 50%
All 66 50 76% 45 68% 56 85% 11 17%
2x2 Contingency Table Values Fisher’s Exact Test P-Values
  Positive Negative ER vs MMR PR vs MMR AR vs MMR
EEC ER 35 1   <0.0001  
PR 35 1 <0.0001   <0.0001
AR 35 1      
MMR 6 30      
NEEC ER 11 15   0.3  
PR 7 19 0.03   0.0001
AR 17 9      
MMR 3 23      
Met ER 4 0   1  
PR 3 1 0.4   0.4
AR 4 0      
MMR 2 2      
All ER 50 16   <0.0001  
PR 45 21 <0.0001   <0.0001
AR 56 10      
MMR 11 55      

ER, estrogen receptor; PR, progesterone receptor; +, positive reaction; AR, androgen receptor; EEC, endometrial endometrioid cancer; NEEC, non-endometrioid endometrial cancers which includes: SCA, serous carcinoma; CCCA, clear cell carcinoma; CS, carcinosarcoma; DECA, dedifferentiated endometrial carcinoma; and MNCA, mesonephric like carcinoma; Met, metastatic carcinoma; MMR, mismatch repair, loss as positive, intact as negative.