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. 2023 Sep 19;18(9):e0291361. doi: 10.1371/journal.pone.0291361

Table 5. Summary of literature review delineating expression of the hormonal receptors in the endometrial malignancies.

Authors Institution Year EEC SCA CCCA CS
  AR ER PR   AR ER PR   AR ER PR   AR ER PR
  Tot +n (+%) +n (+%) +n (+%) Tot +n (+%) +n (+%) +n (+%) Tot +n (+%) +n (+%) +n (+%) Tot +n (+%) +n (+%) +n (+%)
Current series UCLA 2023 36 35 (97) 35 (97) 35 (97) 13 12 (92) 11 (85) 8 (62) 6 3 (50) 0 (0) 0 (0) 6 6 (100) 4 (67) 3 (50)
Cao et al. [23] HNSM 2021 9 6 (67) 6 (67) 2 (20) 8 7 (88) 4 (50) 4 (50) 12 1 (9) 1 (9) 1 (9) 10 8 (80) 8 (80) 6 (60)
Zadeh et al. [4] UVC 2018 20 11 (65) 18 (90) 17 (85) 10 7 (70) 8 (80) 5 (50) 10 3 (30) 6 (60) 1 (10) 10 5 (50) 4 (40) 3 (30)
Tangen et al. [14] UIB 2016 574 386 (67) LP LP 65 36 (55) LP LP 28 7 (25) LP LP 32 13 (41) LP LP
  DECA MNCA Met All
  AR ER PR AR ER PR AR ER PR AR ER PR
  Tot +n (+%) +n (+%) +n (+%) Tot +n (+%) +n (+%) +n (+%) Tot +n (+%) +n (+%) +n (+%) Tot +n (+%) +n (+%) +n (+%)
Current series UCLA 2023 5 0 (0) 0 (0) 0 (0) 1 0 (0) 0 (0) 0 (0) 4 4 (100) 4 (100) 3 (75) 71 60 (85) 54 (76) 49 (69)
Cao et al. [23] HNSM 2021 16 10 (63) NP NP NR NR NR NR NR NR 55 32 (58) 19 (35) 13 (24)
Zadeh et al. [4] UVC 2018 NR NR NR NR NR NR NR NR NR 50 26 (52) 36 (72) 26 (52)
Tangen et al. [14] UIB 2016 13 1 (7) LP LP 0 (0) LP LP Unclear data 712 442 (62) LP LP
Total 888 569 (64) 109 (72) 88 (50)

EEC, endometrial endometrioid cancer; SCA, serous carcinoma; CCCA, clear cell carcinoma; CS, carcinosarcoma; DECA, dedifferentiated/undifferentiated endometrial carcinoma; MNCA, mesonephric like carcinoma; Met, metastatic carcinoma; Tot, total cases; AR, androgen receptor; ER, estrogen receptor; PR, progesterone receptor; +n, number of positives; +%, percentage of positives; NP, Data Not provided; NR, not reported; UCLA, University of California, Los Angeles; HNSM; Donald and Barbara Zucker School of Medicine at Hofstra/Northwell School of Medicine, Hempstead, New York; UVC, University of Virginia, Charlottesville; UIB, University of Bergen, Norway; LP, ER & PR data were lumped together, therefore not represented in this table.