Table 1.
Clinical characteristics and conventional ultrasound parameters of healthy control and PE patients with and without PH before treatment
| Healthy control (n = 40) | PE without PH (n = 39) | PE with PH (n = 34) | |
|---|---|---|---|
| Age, years (mean ± SD) | 55.95 ± 8.84 | 57.36 ± 7.22 | 59.42 ± 9.28 |
| Height (cm) | 162.43 ± 9.12 | 161.07 ± 8.57 | 162.42 ± 7.13 |
| Weight (kg) | 59.33 ± 7.37 | 62.15 ± 8.47 | 61.05 ± 9.31 |
| HR (bpm) | 71.10 ± 10.25 | 72.55 ± 8.46 | 74.19 ± 12.94 |
| Drug history [n(%)] | 11(27.5) | 15(38.46)△ | 19(55.88)△ |
| Systolic pressure | 114 ± 23.27 | 132.35 ± 20.32△ | 141.51 ± 25.66△# |
| Diastolic pressure | 85 ± 10.76 | 95.46 ± 17.34△ | 98.33 ± 19.67△# |
| Hypertension [n(%)] | 8(20) | 11(28.20)* | 14(41.17)△ |
| Diabetes [n(%)] | 9(22.5) | 10(25.64)* | 13(38.23)△ |
| Dyspnea [n(%)] | – | 33(84) | 33(97) |
| Chest tightness [n(%)] | – | 28(72) | 30(88) |
| Hemoptysis [n(%)] | – | 25(64) | 28(83) |
| Syncope [n(%)] | – | 21(54) | 25(74) |
| Wells score | – | 4.1 ± 2.84 | 4.72 ± 1.63 |
| RVDD (mm) | 29.19 ± 6.76 | 32.59 ± 7.82* | 35.77 ± 8.92△# |
| RV FS (%) | 33.52 ± 5.19 | 29.80 ± 6.79* | 23.11 ± 6.37△# |
| RV FAC (%) | 37.31 ± 7.42 | 35.91 ± 6.43* | 30.45 ± 7.37△# |
| RADD (mm) | 32.27 ± 4.11 | 34.14 ± 6.13* | 37.24 ± 6.85△ |
| RV/LV (%) | 0.75 ± 0.44 | 0.88 ± 0.74* | 1.18 ± 0.43△# |
| TAPSE (cm) | 2.49 ± 0.48 | 1.83 ± 0.33△ | 1.62 ± 0.64△# |
Data are expressed as
RVDD right ventricular diastolic diameter, RVFS right ventricular fraction shortening, RVFAC right ventricular fractional area change, RADD right atrium diastolic diameter, RV/LV right ventricular to left ventricular diameter ratio, TAPSE tricuspid annular peak systolic excursion
Compared to control group, *P < 0.05, △P < 0.01
Compared to PE without PH group, #P < 0.05 inPE with PH group