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. Author manuscript; available in PMC: 2023 Sep 28.
Published in final edited form as: Proteomics Clin Appl. 2023 Mar 27;17(5):e2200071. doi: 10.1002/prca.202200071

Figure 1. Differential analysis of proteins identified in sonicate fluids from periprosthetic joint infection (PJI) and non-infectious arthroplasty failure (NIAF) using liquid chromatography–tandem mass spectrometry analysis.

Figure 1.

Volcano plot showing statistically significant proteins differentially abundant in sonicate fluid from PJI cases. Proteins with increased and decreased abundance were indicated in red and blue, respectively. The top five DAPs are labelled. Vertical dashed lines designate log2Fold-change value of ±2-fold and the horizontal dashed line designates a p-value = 0.05. Statistical significance was determined using 2-sample t-test (p-values ≤0.05 and log2fold-change values ≥2 or ≤−2). Data depicted are of NIAF (n=4) and S. aureus PJI (n=4) sonicate fluid samples.