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. 2023 Sep 6;10:1242241. doi: 10.3389/fmed.2023.1242241

Table 2.

Comparison of clinical characteristics before and after sodium-glucose cotransporter 2 inhibitors treatment for three months.

Characteristics Baseline
(n = 93)
Follow-up
(n = 93)
p value
Initial proteinuria, g/24 h
median, IQR
1.32 (1.00 to 2.24) 1.07 (0.65–1.68) <0.001
Albumin, g/L 40.7 ± 4.0 41.4 ± 4.1 0.001
eGFR, ml/min/1.73m2
mean ± SD
58 ± 22 56 ± 21 0.008
SBP, mmHg, mean ± SD 124 ± 12 124 ± 13 0.947
DBP, mmHg, mean ± SD 80 ± 9 79 ± 10 0.326
Urine sodium excretion
median, IQR
162 (126 to 209) 163 (126 to 195) 0.119
Hematuria, RBC/HPF 12.3 (3.5 to 38.2) 8.9 (2.6 to 28.8) 0.001

SD, standard deviation; IQR, interquartile range; eGFR, estimated glomerular filtration rate; SBP, systolic blood pressure; DBP, diastolic blood pressure; RBC, red blood cell; HPF, high-power field.